In your bot's Twitter properties you can configure it to retweet or process/reply to tweets with specific keywords or hashtags.

Normally a bot will perform a Twitter search to find new tweets for it to process. You can configure your bot's Twitter search in its "Tweet Search" property.

You can create a bot to manage a Twitter account, or create a Twitter account for your bot.

First, create your bot, and your Twitter account. Also sign into your Twitter account.